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Thermo Scientific™ Accucore™ PREP XL C18 HPLC Columns
Description
Achieve optimal retention of a broad range of nonpolar analytes across multiple applications with Accucore XL C18 solid-core particles.
Build off of conventional HPLC methods for your scale up purification needs by using Thermo Scientific™ Accucore™ XL C18 preparative HPLC Columns. Rugged 4μm solid-core particles ensure high-efficiencies within low pressure limits requirements. The high bonded phase coverage delivers optimal retention of a comprehensive range of non-polar analytes throughout numerous applications. Our columns come in a wide range of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed.
Optimal Selectivity for Nonpolar Compounds
- Hydrophobic interaction mechanism.
- C18 (USP L1) selectivity.
High-Efficiency Separations for Enhanced Resolution and Sensitivity
- Core-enhanced technology 4μm particles and narrow particle size distribution reduce band broadening and improve separation efficiencies for conventional HPLC methods.
- High surface coverage of silica minimizes secondary interactions and peak tailing.
Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.
Standard Threaded and Standard Flange Hardware
- Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
- Standard threaded hardware for column i.d. < 40mm.
- Standard flange hardware for column i.d. ≥ 40mm.
- Standard hardware can be modified on request to be compatible with SFC.
XtendedLife Hardware
- Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
- Compatible with SFC and is available in dimensions up to 50mm i.d.
Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.
Customer Specific Orders
- If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
- Please contact your local sales representative for Customer Specific Orders.
- Custom built columns are not eligible for returns.

Specifications
Specifications
Column Format | Guard Column |
Diameter (Metric) | 10 mm |
For Use With | Guard Column Requires Use of Preparative Guard Holder, 885-010 |
Length (Metric) | 8 mm |
Max. Pressure | 4300 psi (295 bar) |
Particle Size | 5 μm |
pH | 2 to 9 |
Pore Size | 80 Å |
Surface Area | 90 m²/g |
Temperature | 60°C |
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