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ACD Mouse anti-Human, Clone: OTI2B1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF504379

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.Specifications
ACD | |
Monoclonal | |
Unconjugated | |
ACD | |
PIP1, PTOP, TINT1, TPP1 | |
Mouse | |
Affinity Chromatography | |
RUO | |
65057 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI2B1 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q96AP0 | |
ACD | |
Full length human recombit protein of human ACD produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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