Invitrogen™ ACE Monoclonal Antibody (230214)

Catalog No.	Quantity
PIMA523939	100 μg

Catalog No. PIMA523939 Supplier Invitrogen™ Supplier No. MA523939

Description

Rat Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes-the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

Specifications

• Antigen: ACE
• Applications: Flow Cytometry, Immunoprecipitation
• Classification: Monoclonal
• Clone: 230214
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: Ace
• Gene Accession No.: P09470
• Gene Alias: ACE; ACE1; ACE-T; angiotensin 1 converting enzyme 1; angiotensin converting enzyme; angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme 1; angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript; angiotensin I-converting enzyme (Dipeptidyl carboxypeptidase 1); angiotensin-converting enzyme; Angiotensin-converting enzyme, soluble form; angiotensin-converting enzyme; LOW QUALITY PROTEIN: angiotensin-converting enzyme; angiotensin-converting enzyme-like; AW208573; carboxycathepsin; CD143; CD143 antigen; DCP; Dcp1; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase 1 (Angiotensin I-converting enzyme); dipeptidyl carboxypeptidase I; dipeptidyl peptidase; I79_009670; ICH; kininase II; LOC103158533; MGC26566; MVCD3; peptidase P; peptidyl dipeptidase i; StsRR92; testicular ECA
• Gene Symbols: Ace
• Host Species: Rat
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse ACE/CD143 (aa 35-1264).
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11421
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a