ACE Monoclonal Antibody (OTI2G5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA812212

Catalog No. 50-168-4456

Description

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

Specifications

• Antigen: ACE
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P12821
• Gene Symbols: ACE
• Immunogen: Human recombit protein fragment corresponding to amino acids 642-1230 of human ACE produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2G5
• Conjugate: Unconjugated
• Gene: ACE
• Gene Alias: ACE1, CD143, DCP, DCP1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1636
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid