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  6. 272810

ACET, Tocris Bioscience™

Catalog Number 272810
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Quantity:
10 mg
This item is not returnable. View return policy
936095-50-0
C20H21N3O6S
431.463
OAAMYRWMIRGBQF-UHFFFAOYSA-N
(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2, 4-dione
118797384
3-[[3-(2-amino-2-carboxyethyl)-5-methyl-2,6-dioxo-1,3-diazinan-1-yl]methyl]-5-phenylthiophene-2-carboxylic acid
CC1CN(C(=O)N(C1=O)CC2=C(SC(=C2)C3=CC=CC=C3)C(=O)O)CC(C(=O)O)N
This item is not returnable. View return policy
936095-50-0
C20H21N3O6S
431.463
OAAMYRWMIRGBQF-UHFFFAOYSA-N
(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2, 4-dione
118797384
3-[[3-(2-amino-2-carboxyethyl)-5-methyl-2,6-dioxo-1,3-diazinan-1-yl]methyl]-5-phenylthiophene-2-carboxylic acid
CC1CN(C(=O)N(C1=O)CC2=C(SC(=C2)C3=CC=CC=C3)C(=O)O)CC(C(=O)O)N

Description

Potent kainate antagonist; displays selectivity for GluK1-containing receptors

Potent and selective GluK1 (formerly GluR5) containing kainate receptor antagonist (IC50 = 7 nM) that displays selectivity over GluK2 (formerly GluR6) containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA receptor-independent long term potentiation (LTP) in vitro at nanomolar concentrations.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Quantity 10 mg
Formula Weight 429.45
Percent Purity >98%
Chemical Name or Material ACET

Safety and Handling

Recommended Storage Store at Room Temperature
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