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Invitrogen™ Acetyl-CoA Carboxylase Polyclonal Antibody
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Catalog No. PIPA577844
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100 μL
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PIPA577844 100 μL
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Catalog No. PIPA577844 Supplier Invitrogen™ Supplier No. PA577844
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Description

Rabbit Polyclonal Antibody

Positive Control: 293T, A431, HeLa, HepG2 Predicted Reactivity: Pig (94%), Chicken (83%), Sheep (94%), Rhesus Monkey (98%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Acetyl-CoA Carboxylase
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.55 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Acaca
Gene Accession No. P11497, Q13085, Q5SWU9
Gene Alias A1Z784_DROME; A530025K05Rik; Acac; Acaca; ACACAD; Acc; ACC1; ACCA; ACC-alpha; ACC-PA; ACC-PB; ACC-PC; ACC-PE; ACC-PF; ACC-PG; aceto-acetyl-CoA-thiolase; acetyl CoA carboxylase; acetyl coenzyme A carboxylase; Acetyl-CoA carboxylase; Acetyl-CoA carboxylase 1; acetyl-CoA carboxylase 265; acetyl-CoA carboxylase alpha; acetyl-CoA-carboxylase; acetyl-coenzyme A carboxylase; acetyl-coenzyme A carboxylase alpha; ACoT; Biotin carboxylase; CG11198; CG11198-PA; CG11198-PB; CG11198-PC; CG11198-PE; CG11198-PF; CG11198-PG; CG8723; dACC; DmACC; Dmel\CG11198; Dmel_CG11198; EC 6.3.4.14; EC 6.4.1.2; FBgn0043811; GH12002p; Gm738; I79_006999; unnamed protein product
Gene Symbols Acaca, ACC
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human Acetyl-CoA Carboxylase 1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104371, 107476, 31, 60581
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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