Invitrogen™ H2BK20ac Monoclonal Antibody (GT578)

Catalog No.	Quantity
PIMA531551	100 μL

Catalog No. PIMA531551 Supplier Invitrogen™ Supplier No. MA531551

Description

Mouse Monoclonal Antibody

Keep as concentrated solution. Positive Control: HeLa (0.4 uM Trichoststin A treatment for 18 hr). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.

Specifications

• Antigen: H2BK20ac
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: GT578
• Concentration: 1.1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: H2BW2
• Gene Accession No.: A0A2R8Y619, O60814, P06899, P0C1H6, P23527, P33778, P57053, P58876, P62807, Q16778, Q5QNW6, Q7Z2G1, Q8N257, Q93079, Q96A08, Q99877, Q99879, Q99880
• Gene Alias: 2610022J01Rik; Acetyl-Histone H2; Acetyl-Histone H2B K20; Acetyl-Histone H2B Lys20; AV127319; bA317E16.3; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; GL105; H2B; H2B 291A; H2B 291B; H2b 613; H2B GL105; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B K; H2B type 12; H2B.1; H2B.1A; H2B.1B; H2B.2; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/q; H2B/r; H2B/S; h2B-143; h2B-221; H2b-291b; H2b-613; H2Bb; H2BC10; H2BC4; H2BC6; H2BC7; H2BC8; H2b-f; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFQ; H2BFR; H2bfs; H2BFT; H2BFU; H2BFWT; H2BGL105; H2BJ; H2b-j; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2b-l; H2BLys20ac; H2b-n; H2BQ; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRA-interacting protein 2; HIRIP1; HIRIP2; HIST1H2BA; HIST1H2BB; HIST1H2BC; HIST1H2BD; Hist1h2be; Hist1h2bf; HIST1H2BG; Hist1h2bh; HIST1H2BI; Hist1h2bj; Hist1h2bk; HIST1H2BL; Hist1h2bm; Hist1h2bn; HIST1H2BO; HIST1H3I; Hist2h2be; HIST2H2BF; Hist3h2bb; histone 1, H2ba; histone 1, H2bb; histone 1, H2bc; histone 1, H2bd; histone 1, H2bg; histone 1, H2bh; histone 1, H2bi; histone 1, H2bj; histone 1, H2bk; histone 1, H2bl; histone 1, H2bm; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone 3, H2bb; histone cluster 1, H2ba; histone cluster 1, H2bb; histone cluster 1, H2bc; histone cluster 1, H2bd; histone cluster 1, H2bg; histone cluster 1, H2bh; histone cluster 1, H2bi; histone cluster 1, H2bj; histone cluster 1, H2bk; histone cluster 1, H2bl; histone cluster 1, H2bm; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 2, H2be; histone cluster 2, H2bf; histone cluster 3, H2bb; histone family member; histone H2B; histone H2B type 1-A; Histone H2B type 1-B; histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; histone H2B type 1-D; Histone H2B type 1-F/J/L; histone H2B type 1-H; Histone H2B type 1-J; histone H2B type 1-K; Histone H2B type 1-L; histone H2B type 1-M; Histone H2B type 1-N; histone H2B type 1-O; Histone H2B type 2-E; histone H2B type 2-F; Histone H2B type 3-B; histone H2B type F-M; Histone H2B type F-S; histone H2B type F-S-like; histone H2B type W-T; Histone H2B, testis; Histone H2B.1; histone H2B.1 A; Histone H2B.1 B; histone H2B.2; Histone H2B.a; histone H2B.b; Histone H2B.c; histone H2B.d; Histone H2B.e; histone H2B.f; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.j; histone H2B.k; Histone H2B.l; histone H2B.n; Histone H2B.q; histone H2B.r; Histone H2B.s; histone H2B-GL105; LOC102724334; MGC125414; MGC125415; MGC125416; MGC9388; R74621; RP1-193B12.10; STBP; T25626; testis-specific histone 2b; testis-specific histone H2B; Th2b; TSH2B; TSH2B.1
• Gene Symbols: H2B, H2bc1, H2BC10, H2BC11, H2BC12, H2BC13, H2BC14, H2BC15, H2BC17, H2bc18, H2BC21, H2BC3, H2BC4, H2BC5, H2BC8, H2BC9, H2BE1, H2BU1, H2BW1, H2BW2, LOC102724334
• Host Species: Mouse
• Immunogen: Carrier-protein conjugated synthetic peptide surrounding acetyl Lys20 of human Histone H2B. The exact sequence is proprietary.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 102724334, 114483833, 128312, 158983, 255626, 286436, 3017, 3018, 440689, 8339, 8340, 8341, 8342, 8345, 8346, 8347, 8348, 8349, 85236, 8970
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1