Acetyl-Histone H3 (Lys9, Lys14)Rabbit anti-C. elegans, Chicken, Drosophila, Human, Mouse, Plant, Rat, Xenopus laevis, Polyclonal, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 600401I73

Catalog No. 50-199-2174

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Anti-Histone H3 [ac Lys9, ac Lys14] reacts with human Histone H3.2. A BLAST analysis was used to suggest cross-reactivity with Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology. Cross-reactivity with Histone H3 from other sources has not been determined.

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

• Antigen: Acetyl-Histone H3 (Lys9, Lys14)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H3-3A
• Gene Alias: Acetyl H3; Acetyl Histone H3; Acetyl-H3 K9 K14; Acetyl-H3 Lys9 Lys14; Acetyl-Histone H3 K9 K14; Acetyl-Histone H3 Lys9 Lys14; B0035.7; CELE_T10C6.12; F07B7.10; F07B7.3; F08G2.2; F17E9.13; F35H10.1; F45F2.4; F54E12.5; F55G1.10; H02I12.7; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3 K9acK14ac; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3c10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3f3b; h3f3b.1; h3f3c; h3f3d; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h;
• Host Species: Rabbit
• Regulatory Status: RUO
• Gene ID (Entrez): 117056, 126961, 180073, 260423, 3020, 3021, 318847, 319150, 319152, 333932, 360198, 399088, 440093, 625328, 8350, 8357, 8358, 8968, 97114
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ChIP Assay, Dot Blot, Immunofluorescence, Immunohistochemistry, Western Blot
• Concentration: 0.63 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl, 30% glycerol and 0.05% sodium azide; pH 7.2
• Gene Accession No.: P02301, P09588, P68431, P68433, P84228, P84243, P84245, Q6NXT2, Q71DI3
• Gene Symbols: H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7, h3c8.S, his-3, His3:CG31613
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: C. elegans, Chicken, Drosophila, Human, Mouse, Plant, Rat, X. laevis
• Product Type: Antibody