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MilliporeSigma™ acetyl-Histone H3 (Lys9), Rabbit, Alexa Fluor 555, Polyclonal,

Catalog No. 06942AF555 Shop All MilliporeSigma Products
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Quantity:
100 μL
Conjugate:
Alexa Fluor 555
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Catalog No. Quantity Conjugate
06942AF555 100 μL Alexa Fluor 555
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Catalog No. 06942AF555 Supplier MilliporeSigma™ Supplier No. 06942AF555
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Description

Rabbit Polyclonal Antibody

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the &primebeads on a string&prime structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Histone H3 variants (H3.1, H3.2 and H3.3) have been implicated in the epigenetic memory of cellular state. Genome-wide patterns of H3 are dependent on amino acid sequence and change with cellular differentiation at developmentally regulated loci.
TRUSTED_SUSTAINABILITY

Specifications

Antigen acetyl-Histone H3 (Lys9)
Applications Immunocytochemistry
Classification Polyclonal
Concentration Please refer to lot specific datasheet.
Conjugate Alexa Fluor 555
Formulation Purified rabbit polyclonal antibody in PBS with 1.5% BSA with 0.05% Sodium Azide.
Gene HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ
Gene Accession No. P68431
Host Species Rabbit
Immunogen KLH-conjugated synthetic peptide (ARTKQTARK(Ac)STG-C) corresponding to amino acids 1-12 of histone H3 with acetylated Lys9.
Purification Method Protein A Purified
Quantity 100 μL
Regulatory Status RUO
Research Discipline Epigenetics & Nuclear Function
Primary or Secondary Primary
Gene ID (Entrez) NP_003520
Test Specificity Histone H3 acetylated at position 9.
Target Species Human
Content And Storage Stable for 1 year at 2°-8°C from date of receipt.
Form Purified
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For Research Use Only. Not for use in diagnostic procedures.

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