Invitrogen™ H4ac pan-acetyl (K5,K8,K12,K16) Monoclonal Antibody (3HH4-2C2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA3066

Catalog No. PIMA3066

Description

MA3-066 detects acetylated histone H4 at Lysines 5, 8, 12 or 16 in human samples MA3-066 has successfully been used in western blot, immunofluoresecence and immunoprecipitation applications. Immunogen is a synthetic peptide conjugated to ovalbumin corresponding to residues 1 to 24 of human histone H4 which is conserved in a wide range of species.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: H4ac pan-acetyl (K5,K8,K12,K16)
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.05% sodium azide
• Gene Accession No.: P62805
• Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
• Immunogen: Ovalbumin conjugated synthetic peptide (MSGRG(acetyl-K)GG(acetyl-K)GLG(acetyl-K)GGA(acetyl-K)RHRKVLRC) corresponding to residues 1 to 24 of human histone H4.
• Regulatory Status: RUO
• Gene ID (Entrez): 121504, 8294, 8359, 8363, 8366, 8367, 8370
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 3HH4-2C2
• Conjugate: Unconjugated
• Gene: H4C1
• Gene Alias: acetyl Histone H4; Acetyl-H4 K5 K8 K12 K16; Acetyl-H4 Lys5 Lys8 Lys12 Lys16; Acetyl-Histone H4 K5 K8 K12 K16; Acetyl-Histone H4 Lys5 Lys8 Lys12 Lys16; FO108; H4; H4 ac pan-acetyl; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4ac; H4c1; H4c11; H4C12; H4C13; H4c14; H4C15; H4c2; H4c3; H4c4; H4C5; H4c6; H4C8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K12; H4K12a; H4K12ac; H4K16; H4K16ac; H4K5; H4K5,8,12,16ac; H4K5ac; H4K8; H4K8ac; H4Lys5,8,12,16ac; H4M; HIST1H4; HIST1H4A; Hist1h4b; HIST1H4C; Hist1h4d; HIST1H4E; Hist1h4f; Hist1h4h; Hist1h4i; HIST1H4J; Hist1h4k; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; histone H4; Histone H4 acetyl; Histone H4A; Histone H4K12; Histone H4K16; Histone H4K5; Histone H4K8; histone IV, family 2; X04652
• Host Species: Mouse
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1