Invitrogen™ H4K8ac Monoclonal Antibody (GT478)

Catalog No.	Quantity
PIMA531553	100 μL

Catalog No. PIMA531553 Supplier Invitrogen™ Supplier No. MA531553

Description

Mouse Monoclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (100%), Xenopus laevis (100%). Positive Control: HeLa, HeLa (0.4uM Trichostatin A for 18 hr). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: H4K8ac
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: GT478
• Concentration: 0.95 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: H4C1
• Gene Accession No.: P62805, P62806
• Gene Alias: acetyl Histone H4; Acetyl-H4 K8; Acetyl-H4 Lys8; Acetyl-Histone H4 K8; Acetyl-Histone H4 Lys8; CELE_T10C6.11; F07B7.11; F07B7.4; F45F2.12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K8ac; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4c11; H4C12; H4C13; H4C14; H4C15; H4c2; H4c3; H4C4; H4C5; H4c6; H4C8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K8; H4Lys8ac; H4M; his-20; his-22; his-4; his-52; his-54; his-8; HIST1H4; HIST1H4A; Hist1h4b; HIST1H4C; Hist1h4d; HIST1H4E; HIST1H4F; HIST1H4H; Hist1h4i; Hist1h4j; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; Histone H2B 2; Histone H4; Histone H4 acetyl; Histone H4A; Histone H4K8; Histone H4K8ac; histone IV, family 2; K06C4.12; K06C4.4; T10C6.11; X04652
• Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
• Host Species: Mouse
• Immunogen: Carrier-protein conjugated synthetic peptide surrounding acetyl Lys8 of human Histone H4. The exact sequence is proprietary.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 121504, 319158, 326619, 326620, 8294, 8359, 8363, 8366, 8367, 8370, 97122
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG3