Invitrogen™ H4K8ac Recombinant Rabbit Monoclonal Antibody (8H5L4), ChIP-Verified

Catalog No.	Quantity
PI701796	100 μg

Catalog No. PI701796 Supplier Invitrogen™ Supplier No. 701796

Description

Rabbit Recombinant Monoclonal Antibody

Since it is highly conserved across species, the antibody may react with many other species. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: H4K8ac
• Applications: Peptide Array, ChIP Assay, Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 8H5L4
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene: H4C1
• Gene Accession No.: P62805
• Gene Alias: acetyl Histone H4; Acetyl-H4 K8; Acetyl-H4 Lys8; Acetyl-Histone H4 K8; Acetyl-Histone H4 Lys8; CELE_T10C6.11; F07B7.11; F07B7.4; F45F2.12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K8ac; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4c11; H4C12; H4C13; H4C14; H4C15; H4c2; H4c3; H4C4; H4C5; H4c6; H4C8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K8; H4Lys8ac; H4M; his-20; his-22; his-4; his-52; his-54; his-8; HIST1H4; HIST1H4A; Hist1h4b; HIST1H4C; Hist1h4d; HIST1H4E; HIST1H4F; HIST1H4H; Hist1h4i; Hist1h4j; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; Histone H2B 2; Histone H4; Histone H4 acetyl; Histone H4A; Histone H4K8; Histone H4K8ac; histone IV, family 2; K06C4.12; K06C4.4; T10C6.11; X04652
• Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
• Host Species: Rabbit
• Immunogen: Acetylated peptide (Lys8) corresponding to Human H4 (aa 6-13).
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 121504, 8294, 8359, 8363, 8366, 8367, 8370
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov