Invitrogen™ Acetylated Lysine Polyclonal Antibody

Catalog No.	Quantity
PIPA5114810	100 μL

Catalog No. PIPA5114810 Supplier Invitrogen™ Supplier No. PA5114810

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Acetyl-Lysine Antibody only when acetylated at Lysine Antibody.

In the nucleus, DNA is tightly packed into nucleosomes generating an environment which is highly repressive towards DNA processes such as transcription. Acetylation of lysine residues within proteins has emerged as an important mechanism used by cells to overcome this repression. The acetylation of non-histone proteins such as transcription factors, as well as histones appears to be involved in this process. Acetylation may result in structural transitions as well as specific signaling within discrete chromatin domains. The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain. Furthermore, recent findings suggest that bromodomain/acetylated-lysine recognition can serve as a regulatory mechanism in protein-protein interactions in numerous cellular processes such as chromatin remodeling and transcriptional activation.

Specifications

• Antigen: Acetylated Lysine
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Alias: Acetyl Lysine; Acetylated Lysine; Acetyllysine
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human Lysine Antibody around the acetylation site of Lysine Antibody.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Chemical, Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG
• Target Molecule: Chemical