Invitrogen™ Acetylated Lysine Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114810

Catalog No. PIPA5114810

Description

Antibody detects endogenous levels of Acetyl-Lysine Antibody only when acetylated at Lysine Antibody.

In the nucleus, DNA is tightly packed into nucleosomes generating an environment which is highly repressive towards DNA processes such as transcription. Acetylation of lysine residues within proteins has emerged as an important mechanism used by cells to overcome this repression. The acetylation of non-histone proteins such as transcription factors, as well as histones appears to be involved in this process. Acetylation may result in structural transitions as well as specific signaling within discrete chromatin domains. The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain. Furthermore, recent findings suggest that bromodomain/acetylated-lysine recognition can serve as a regulatory mechanism in protein-protein interactions in numerous cellular processes such as chromatin remodeling and transcriptional activation.

Specifications

• Antigen: Acetylated Lysine
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: Acetyl Lysine; Acetylated Lysine; Acetyllysine
• Immunogen: A synthesized peptide derived from human Lysine Antibody around the acetylation site of Lysine Antibody.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Form: Liquid
• Target Molecule: Chemical

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Target Species: Chemical, Human
• Product Type: Antibody
• Isotype: IgG