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ACHP, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
This item is not returnable. View return policy
406208-42-2
C21H24N4O2
364.449
DWQVGCQPWXKRKO-JZJYNLBNSA-N
achp,2-amino-6-2-cyclopropylmethoxy-6-hydroxyphenyl-4-4-pipe
22258733
(6E)-2-amino-6-[2-(cyclopropylmethoxy)-6-oxocyclohexa-2,4-dien-1-ylidene]-4-piperidin-4-yl-1H-pyridine-3-carbonitrile
C1CC1COC2=CC=CC(=O)C2=C3C=C(C(=C(N3)N)C#N)C4CCNCC4
This item is not returnable. View return policy
406208-42-2
C21H24N4O2
364.449
DWQVGCQPWXKRKO-JZJYNLBNSA-N
achp,2-amino-6-2-cyclopropylmethoxy-6-hydroxyphenyl-4-4-pipe
22258733
(6E)-2-amino-6-[2-(cyclopropylmethoxy)-6-oxocyclohexa-2,4-dien-1-ylidene]-4-piperidin-4-yl-1H-pyridine-3-carbonitrile
C1CC1COC2=CC=CC(=O)C2=C3C=C(C(=C(N3)N)C#N)C4CCNCC4

Selective IKKα and IKKβ inhibitor

IκB kinase inhibitor (IC50 values are 8.5 and 250 nM for IKKβ and IKKα respectively). Selective for IKKα and IKKβ over IKK3, Syk and MAPKKK4 (IC50 values are > 20 μM). Inhibits DNA binding activity of NF-κB. Blocks NF-κB pathway in multiple myeloma cell lines; induces cell growth arrest and apoptosis.

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Quantity 10mg
Formula Weight 364.44
Percent Purity >97%
Chemical Name or Material ACHP

Recommended Storage : Store at -20°C