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Invitrogen™ ACMSD Monoclonal Antibody (3A9)
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Catalog No. PIMA523009
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100 μg
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Catalog No. Quantity
PIMA523009 100 μg
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Catalog No. PIMA523009 Supplier Invitrogen™ Supplier No. MA523009
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Description

Mouse Monoclonal Antibody

Peptide Sequence: SHGFSMRPDL CAQDNPMNPK KYLGSFYTDA LVHDPLSLKL LTDVIGKDKV ILGTDYPFPL GELEPGKLIE SMEEFDEETK NKLKAGNALA FLGLERKQFE.

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004].
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACMSD
Applications ELISA, Western Blot
Classification Monoclonal
Clone 3A9
Concentration 0.2-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene ACMSD
Gene Accession No. Q8TDX5
Gene Alias 2-amino-3-carboxylmuconate-6-semialdehyde decarboxylase; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Acmsd; amino carboxymuconate semialdehyde decarboxylase; aminocarboxymuconate semialdehyde decarboxylase; Picolinate carboxylase; zgc:162888
Gene Symbols ACMSD
Host Species Mouse
Immunogen ACMSD (NP_612199, 179 a.a. ~ 278 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 130013
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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