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Invitrogen™ ACMSD Polyclonal Antibody
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Catalog No. PIPA582392
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100 μL
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PIPA582392 100 μL
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Catalog No. PIPA582392 Supplier Invitrogen™ Supplier No. PA582392
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GVFEKFPKLK VCFAHGGGAF PFTVGRISHG FSMRPDLCAQ DNPMNPKKYL GSFYTDALVH DPLSLKLLTD VIGKDKVILG TDYPFPLGEL EPGKLIESME EFDEETKNKL KAGNAL Highest antigen sequence indentity to the following orthologs: Rat - 87%, Mouse - 90%.

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004].
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACMSD
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ACMSD
Gene Accession No. Q8TDX5
Gene Alias 2-amino-3-carboxylmuconate-6-semialdehyde decarboxylase; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Acmsd; amino carboxymuconate semialdehyde decarboxylase; aminocarboxymuconate semialdehyde decarboxylase; Picolinate carboxylase; zgc:162888
Gene Symbols ACMSD
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ACMSD. Recombinant protein control fragment (Product #RP-90368).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 130013
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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