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Invitrogen™ ACMSD Polyclonal Antibody
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Catalog No. PIPA590853
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100 μL
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PIPA590853 100 μL
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Catalog No. PIPA590853 Supplier Invitrogen™ Supplier No. PA590853
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MKIDIHSHIL PKEWPDLKKR FGYGGWVQLQ HHSKGEAKLL KDGKVFRVVR ENCWDPEVRI REMDQKGVTV QALSTVPVMF SYWAKPEDTL NLCQLLNNDL ASTVVSYPRR FVGLGTLPMQ APELAVKEME RCVKELGFPG VQIGTHVNEW DLNAQELFPV YAAAERLKCS LFVHPWDMQM DGRMAKYWLP WLVGMPAETT IAICSMIMGG VFEKFPKLKV CFAHGGGAFP FTVGRISHGF SMRPDLCAQD NPMNPKKYLG SFYTDALVHD PLSLKLLTDV IGKDKVILGT DYPFPLGELE PGKLIESMEE FDEETKNKLK AGNALAFLGL ERKQFE; Positive Samples: Mouse kidney, Mouse liver, Rat kidney.

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004].
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACMSD
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene ACMSD
Gene Accession No. Q8R519, Q8R5M5
Gene Alias 2-amino-3-carboxylmuconate-6-semialdehyde decarboxylase; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Acmsd; amino carboxymuconate semialdehyde decarboxylase; aminocarboxymuconate semialdehyde decarboxylase; Picolinate carboxylase; zgc:162888
Gene Symbols ACMSD
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human ACMSD (NP_6121992).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171385, 266645
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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