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Invitrogen™ acnB Monoclonal Antibody (4C2B3)
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Catalog No. PIMA528967
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100 μL
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PIMA528967 100 μL
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Catalog No. PIMA528967 Supplier Invitrogen™ Supplier No. MA528967
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for E. coli acnB.

acnB is involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2-methylcitrate cycle I (propionate degradation route). It catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch. AcnB also decreases the stability of the sodA transcript.
TRUSTED_SUSTAINABILITY

Specifications

Antigen acnB
Applications ELISA, Western Blot
Classification Monoclonal
Clone 4C2B3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Alias ACN; Aconitase
Host Species Mouse
Immunogen Recombinant E. coli acnB protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Bacteria
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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