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Invitrogen™ ACOT2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA550905
Description
ACOT2 Polyclonal Antibody detects endogenous levels of ACOT2 protein.
Acyl-CoA thioesterases (ACOTs) are a group of enzymes that catalyze the hydrolysis of acyl-CoA to form coenzyme A (CoA) and a free fatty acid. Through their catalytic activity, ACOTs are able to regulate the level of fatty acids and acyl-CoAs within the cell. ACOT1 (acyl-CoA thioesterase 1, also known as CTE1) and ACOT2 (acyl-CoA thioesterase 2, also known as PTE2) are members of the ACOT family and exhibit different cellular localization, with ACOT1 existing as a monomer in the cytoplasm and ACOT2 localized primarily to mitochondria. Characteristic of most ACOT proteins, ACOT1 and ACOT2 catalyze the conversion of Palmitoyl-CoA and water to free CoA and palmitate, a reaction that is important for the regulation of intercellular fatty acid levels. ACOT2 is expressed as multiple alternatively spliced isoforms and, like ACOT1, is encoded by a gene which maps to human chromosome 14.
Specifications
ACOT2 | |
Polyclonal | |
Unconjugated | |
ACOT2 | |
AA571646; Acot2; Acyl coenzyme A thioester hydrolase; acyl-CoA thioesterase 2; Acyl-coenzyme A thioester hydrolase 2a; acyl-coenzyme A thioesterase 2, mitochondrial; ARTISt/p43; CTE Ia; CTE1A; CTE-Ia; long-chain acyl-CoA thioesterase 2; mitochondrial acyl-CoA thioesterase 1; Mte1; MTE-I; peroxisomal long-chain acyl-coA thioesterase 2; PTE2; PTE2A; Very-long-chain acyl-CoA thioesterase; ZAP128 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
10965 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P49753 | |
ACOT2 | |
Synthesized peptide derived from the Internal region of human ACOT2 (aa 171-220). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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