Invitrogen™ ACOX1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529124

Catalog No. PIPA529124

Description

Recommended positive controls: HepG2. Predicted reactivity: Mouse (88%), Rat (89%), Pig (91%), Chicken (82%), Rhesus Monkey (100%), Bovine (92%), Guinea pig (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: ACOX1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACOX1
• Gene Alias: Acox; Acox1; acyl-CoA oxidase 1; acyl-CoA oxidase 1, palmitoyl; acyl-CoA oxidase, straight-chain; acyl-Coenzyme A oxidase 1, palmitoyl; AOX; D130055E20Rik; PALMCOX; palmitoyl-CoA oxidase; Paox; Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain; Peroxisomal acyl-coenzyme A oxidase 1; peroxisomal fatty acyl-CoA oxidase; peroxisomal fatty acyl-coenzyme A oxidase; peroxisomal straight-chain Acyl-CoA oxidase; RATACOA1; SCOX; Straight-chain acyl-CoA oxidase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11430, 50681, 51
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.89 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P07872, Q15067, Q9R0H0
• Gene Symbols: ACOX1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 216 and 481 of Human ACOX1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov