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Invitrogen™ ACP1 Polyclonal Antibody

Catalog No. PIPA5122294
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200 μL
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PIPA5122294 20 μL
PIPA5118924 200 μL
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Catalog No. PIPA5122294 Supplier Invitrogen™ Supplier No. PA5122294
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Description

Rabbit Polyclonal Antibody

ACP1 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Low molecular weight protein tyrosine phosphtases, including the human red cell phosphatase, HCPTP, are widely expressed cytosolic proteins of approximately 18 kDa that exist in distinct isoforms and are highly selective for phosphotyrosine over phosphoserine or phosphotyrosine. The HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta are fast and slow forms of red cell acid phosphatase5. Like other tyrosine phosphatases, HCPTP is sensitive to inhibition by vanadate, and has a catalytic mechanism that involves formation of a cystinylphosphate intermediate6. The crystal structure of the bovine heart derived enzyme BHPTP shows a four-stranded central parallel b sheet with flanking a helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACP1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene ACP1
Gene Accession No. P24666, P41498
Gene Alias 4632432E04Rik; acid phosphatase; acid phosphatase 1; acid phosphatase 1, soluble; acid phosphatase of erythrocyte; acp1; Acp-1; Acp1-PA; adipocyte acid phosphatase; Adult cuticle protein 1; AI427468; CG7216; CG7216-PA; cytoplasmic phosphotyrosyl protein phosphatase; Dacp-1; Dmel\CG7216; Dmel_CG7216; HAAP; HAAP betaÊ; hypothetical protein; LMW-PTP; LMW-PTPase; LMW-PTP-I low molecular weight phosphotyrosine protein phosphatase isozyme 1; Low molecular weight cytosolic acid phosphatase; low molecular weight phosphotyrosine protein phosphatase; MGC111030; MGC3499; phosphatase 1, soluble; protein tyrosine phosphatase; ptpase; RCJMB04_11a4; Red cell acid phosphatase 1; RH03221p; testicular secretory protein Li 37; Unknown (protein for MGC:128334)
Gene Symbols ACP1
Host Species Rabbit
Immunogen Recombinant protein Acid Phosphatase 1. The antigen corresponds to amino acid range 1-158 of the target protein.
Purification Method Antigen affinity chromatography, Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24161, 52
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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