Invitrogen™ Acrosin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561804

Catalog No. PIPA561804

Description

Immunogen sequence: LMEARVDLID LDLCNSTQWY NGRVQPTNVC AGYPVGKIDT CQ Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

Specifications

• Antigen: Acrosin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACR
• Gene Alias: 53 kDa fucose-binding protein; Acr; Acro; Acrosin; Acrosin heavy chain; acrosin light and heavy chain prepropeptide; Acrosin light chain; acrosin precursor (EC 3.4.21.10); acrosin prepropeptide; ACRS; preproacrosin; proacrosin
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 49
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.30 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P10323
• Gene Symbols: ACR
• Immunogen: Recombinant protein corresponding to Human Acrosin. Recombinant protein control fragment (Product #RP-99045).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG