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Invitrogen™ Acrosin Polyclonal Antibody
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Catalog No. PIPA599580
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100 μL
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PIPA599580 100 μL
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Catalog No. PIPA599580 Supplier Invitrogen™ Supplier No. PA599580
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Acrosin.

ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Acrosin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ACR
Gene Accession No. P10323
Gene Alias 53 kDa fucose-binding protein; Acr; Acro; Acrosin; Acrosin heavy chain; acrosin light and heavy chain prepropeptide; Acrosin light chain; acrosin precursor (EC 3.4.21.10); acrosin prepropeptide; ACRS; preproacrosin; proacrosin
Gene Symbols ACR
Host Species Rabbit
Immunogen A synthesized peptide derived from human ACR(Accession P10323), corresponding to amino acid residues T7-M57.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 49
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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