Invitrogen™ Acrosomal Vesicle Protein Monoclonal Antibody (5E3D6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA538635

Catalog No. PIMA538635

Description

This antibody has been tested in indirect ELISA.

This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.

Specifications

• Antigen: Acrosomal Vesicle Protein
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P26436
• Gene Symbols: ACRV1
• Immunogen: Purified recombinant fragment of human SP10 (aa: 22-265) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5E3D6
• Conjugate: Unconjugated
• Gene: ACRV1
• Gene Alias: acrosomal protein SP-10; Acrosomal vesicle protein 1; Acrv1; D11S4365; Msa63; MSA-63; rSP10; Sp10; SP-10; SPACA2; sperm membrane protein; sperm protein 10
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 56
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov