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Invitrogen™ Acrosomal Vesicle Protein Polyclonal Antibody
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Catalog No. PIPA596930
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100 μL
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PIPA596930 100 μL
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Catalog No. PIPA596930 Supplier Invitrogen™ Supplier No. PA596930
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QPNELSGSID HQTSVQQLPG EFFSLENPSD AEALYETSSG LNTLSEHGSS EHGSSKHTVA EHTSGEHAES EHASGEPAAT EHAEGEHTVG EQPSGEQPSG EHLSGEQPLS ELESGEQPSD EQPSGEHGSG EQPSGEQASG EQPSGEHASG EQASGAPISS TSTGTILNCY TCAYMNDQGK CLRGEGTCIT QNSQQCMLKK IFEGGKLQFM VQGCENMCPS MNLFSHGTRM QIICCRNQSF CNKI; Positive Samples: Mouse pancreas; Cellular Location: Cytoplasmic vesicle, acrosome, secretory vesicle.

This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Acrosomal Vesicle Protein
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ACRV1
Gene Accession No. P26436, P50289
Gene Alias acrosomal protein SP-10; Acrosomal vesicle protein 1; Acrv1; D11S4365; Msa63; MSA-63; rSP10; Sp10; SP-10; SPACA2; sperm membrane protein; sperm protein 10
Gene Symbols ACRV1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 22-265 of human ACRV1 (NP_0016031).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60353
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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