Invitrogen™ ACSL3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588208

Catalog No. PIPA588208

Description

Positive Samples: HeLa, Mouse kidney; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Mitochondrion outer membrane, Peroxisome membrane, Single-pass type III membrane protein Immunogen sequence: CEMENEVLKV LSEAAISASL E.

An initial reaction in fatty acid metabolism in eukaryotic cells is activation of fatty acids catalyzed by acyl-CoA synthetase. FACL3 (fatty acid CoA ligase, long-chain 3) is identified as member of the acyl-CoA synthetase (ACS) family by PCR of rat brain cDNAs using primers based on the conserved region of the ACS protein. The 720-amino acid rat protein preferentially utilizes myristate, laurate, arachidonate, and eicosapentaenoate, and is expressed primarily in brain. The predicted 720-amino acid FACL3 human protein is 92% identical to that of rat.

Specifications

• Antigen: ACSL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACSL3
• Gene Alias: 2610510B12Rik; Acs3; Acsl3; acyl-CoA synthetase long chain family member 3; acyl-CoA synthetase long-chain family member 3; Arachidonate--CoA ligase; Brain acyl-CoA synthetase II; C85929; FACL3; fatty acid Coenzyme A ligase, long chain 3; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; LACS3; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 3; Long-chain-fatty-acid--CoA ligase 3; Pro2194
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114024, 2181, 74205
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.53 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O95573, Q63151, Q9CZW4
• Gene Symbols: ACSL3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 621-720 of human ACSL3 (NP_0044482).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov