Invitrogen™ ACSL4 Recombinant Rabbit Monoclonal Antibody (4W3T9)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542756

Catalog No. PIMA542756

Description

Positive test controls include: 293T, HepG2, Mouse liver, Rat liver. The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome membrane, Mitochondrion outer membrane, Peroxisome membrane, Single-pass type III membrane protein. Immunogen sequence: MAKRIKAKPT SDKPGSPYRS VTHFDSLAVI DIPGADTLDK LFDHAVSKFG KKDSLGTREI LSEENEMQPN GKVFKKLILG NYKWMNYLEV NRRVNNFGSG LTALGLKPKN TIAIFCETRA EWMIAAQTCF KYNFPLVTLY ATLGKEAVVH GLNESEASYL ITSVELLESK LKTALLDISC VKHIIYVDNK AINKAEYPEG FEIHSMQSVE ELGSNPENLG IPPSRPTPSD MAIVMYTSGS TGRPKGVMMH HSNLIAGMTG QCERIPGLGP KDTYIGYLPL.

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.

Specifications

• Antigen: ACSL4
• Classification: Recombinant Monoclonal
• Concentration: 0.6 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: O35547, O60488, Q9QUJ7
• Gene Symbols: Acsl4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 42-321 of human ACSL4 (NP_0752661).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 4W3T9
• Conjugate: Unconjugated
• Gene: Acsl4
• Gene Alias: 9430020A05Rik; Acs4; ACSL4; acyl-CoA synthetase 4; acyl-CoA synthetase long-chain family member 4; Arachidonate--CoA ligase; AU018108; Facl4; fatty acid Coenzyme A ligase, long chain 4; fatty acid-Coenzyme A ligase long chain 4; fatty acid-Coenzyme A ligase, long chain 4; fatty-acid-Coenzyme A ligase, long-chain 4; L MRX63; LACS 4; Lacs4; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; long-chain-fatty-acid--CoA ligase 4; mACS4; MRX63; MRX68
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113976, 2182, 50790
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid