Invitrogen™ ACSL5 Monoclonal Antibody (CL0275)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524595

Catalog No. PIMA524595

Description

Immunogen sequence: VHIVNKADIA MVICDTPQKA LVLIGNVEKG FTPSLKVIIL MDPFDDDLKQ RGEKSGIEIL SLYDAENLGK EHFRKPVPPS PEDLSVICFT SGTTGDPK Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 55%. Binds to an epitope located within the peptide sequence MDPFDDDLKQ as determined by overlapping synthetic peptides.

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: ACSL5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9ULC5
• Gene Symbols: ACSL5
• Immunogen: Recombinant protein corresponding to Human ACSL5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CL0275
• Conjugate: Unconjugated
• Gene: ACSL5
• Gene Alias: 1700030F05Rik; ACS2; ACS5; Acsl5; acyl-CoA synthetase 5; acyl-CoA synthetase long chain family member 5; acyl-CoA synthetase long-chain family member 5; Arachidonate--CoA ligase; FACL5; FACL5 for fatty acid coenzyme A ligase 5; fatty acid coenzyme A ligase 5; fatty acid Coenzyme A ligase, long chain 5; fatty-acid-Coenzyme A ligase, long-chain 5; HGNC:16526; LACS 5; Long-chain acyl-CoA synthetase 5; long-chain fatty acid coenzyme A ligase 5; long-chain-fatty-acid--CoA ligase 5; UNQ633/PRO1250; zgc:92083
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 51703
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid