Invitrogen™ ACTA1/ACTA2/ACTC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100907

Catalog No. PIPA5100907

Description

Antibody detects endogenous levels of total ACTA1/A2/C1.

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Specifications

• Antigen: ACTA1/ACTA2/ACTC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Acta1
• Gene Alias: 0610041G09Rik; AA959943; AAT6; Acta; Acta1; Acta2; Acta-2; ACTC; ACTC1; Actc-1; actin alpha 1; actin alpha cardiac; actin alpha cardiac 1; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; Acts; ACTSA; Actsk-1; Actvs; alpha-actin cardiac; alpha-actin-1; Alpha-actin-2; alphac-actin; alpha-cardiac actin; alphaSMA; ASD5; ASMA; a-SMA; cell growth-inhibiting gene 46 protein; CFTD; CFTD1; CFTDM; CMD1R; CMH11; GIG46; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; SMalphaA; smooth muscle alpha-actin
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11459, 11464, 11475, 29275, 29437, 58, 59, 70, 81633
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P62736, P62737, P62738, P68032, P68033, P68035, P68133, P68134, P68136
• Gene Symbols: Acta1, ACTA2, Actc1
• Immunogen: A synthesized peptide derived from human ACTA1(Accession P68133), corresponding to amino acid residues M1-P34.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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