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Invitrogen™ ACTA1/ACTA2/ACTC1 Polyclonal Antibody
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Catalog No. PIPA5100907
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PIPA5100907 100 μL
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Catalog No. PIPA5100907 Supplier Invitrogen™ Supplier No. PA5100907
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ACTA1/A2/C1.

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACTA1/ACTA2/ACTC1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Acta1
Gene Accession No. P62736, P62737, P62738, P68032, P68033, P68035, P68133, P68134, P68136
Gene Alias 0610041G09Rik; AA959943; AAT6; Acta; Acta1; Acta2; Acta-2; ACTC; ACTC1; Actc-1; actin alpha 1; actin alpha cardiac; actin alpha cardiac 1; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; Acts; ACTSA; Actsk-1; Actvs; alpha-actin cardiac; alpha-actin-1; Alpha-actin-2; alphac-actin; alpha-cardiac actin; alphaSMA; ASD5; ASMA; a-SMA; cell growth-inhibiting gene 46 protein; CFTD; CFTD1; CFTDM; CMD1R; CMH11; GIG46; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; SMalphaA; smooth muscle alpha-actin
Gene Symbols Acta1, ACTA2, Actc1
Host Species Rabbit
Immunogen A synthesized peptide derived from human ACTA1(Accession P68133), corresponding to amino acid residues M1-P34.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11459, 11464, 11475, 29275, 29437, 58, 59, 70, 81633
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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