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Invitrogen™ ACTA1 Monoclonal Antibody (3H5)
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Catalog No. PIMA549215
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100 μg
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PIMA549215 100 μg
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Catalog No. PIMA549215 Supplier Invitrogen™ Supplier No. MA549215
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Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Immunogen sequence is identical to the related mouse and rat sequences. Positive Control - WB: human HepG2 whole cell, human SK-OV-3 whole cell, human PANC-1 whole cell, human Hela whole cell, human A549 whole cell, rat PC-12 whole cell, mouse NIH/3T3 whole cell, mouse HEPA1-6 whole cell. IHC: human bladder cancer tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACTA1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3H5
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene ACTA1
Gene Accession No. P68133, P68134, P68136
Gene Alias AA959943; ACTA; Acta1; Acta-2; actin alpha 1; actin alpha 1, skeletal muscle; actin, alpha 1, skeletal muscle; actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; Acts; Actsk-1; alpha actin 1; alpha-actin-1; ASMA; beta actin; CFTD; CFTD1; CFTDM; cytoplasmic beta-actin; LOW QUALITY PROTEIN: actin, alpha skeletal muscle; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; skeletal alpha actin; unnamed protein product
Gene Symbols ACTA1
Host Species Mouse
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human Actin (277-308aa HETTYNSIMKCDIDIRKDLYANNVMSGGTTMY).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11459, 29437, 58
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG1
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