ACTA2/smooth muscle actin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-3992	Proteintech Group Inc 230811AP150UL	150 μL

Description

This antibody is specific to the ACTA2. It selectively stains the vascular smooth muscle but not cardiac or skeletal muscle.

Among the six actin isoforms described in mammals, two are found in virtually all cells (b- and g-cytoplasmic), two are detected in smooth muscle cells (a- and g-smooth muscle) and two are present in striated muscles, one predomitly in skeletal (a-skeletal) and one in cardiac (a-cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus and the sequences of each of them are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown to appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases.

Specifications

• Antigen: ACTA2/smooth muscle actin
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P62736, P62737, P62738
• Gene ID (Entrez): 11475, 59, 81633
• Immunogen: ACTA2/smooth muscle actin Fusion Protein Ag19481
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ACTA2

• Concentration: 0.17 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: a SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, ACTA2 specific, Actin, aortic smooth muscle, ACTSA, ACTVS, Alpha actin 2, Alpha SMA, a-SMA
• Gene Symbols: ACTA2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody