Invitrogen™ alpha-Cardiac Actin Recombinant Rabbit Monoclonal Antibody (RM257)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA527887

Catalog No. PIMA527887

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

ACTC1 are part of actins, which are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Specifications

• Antigen: alpha-Cardiac Actin
• Classification: Recombinant Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
• Gene Accession No.: P68032, P68033, P68035, Q3ZC07
• Gene Symbols: ACTC1
• Immunogen: A synthetic peptide corresponding to the N-terminus of human alpha-cardiac actin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: RM257
• Conjugate: Unconjugated
• Gene: ACTC1
• Gene Alias: ACTC; Actc1; Actc-1; actin alpha cardiac; actin alpha cardiac 1; actin alpha cardiac muscle 1; actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle; actin, alpha, cardiac muscle 1; alpha-actin cardiac; alphac-actin; alpha-cardiac actin; ASD5; B-actin; cardiac muscle alpha actin 1; CMD1R; CMH11; LVNC4
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11464, 29275, 533219, 70
• Content And Storage: -20°C
• Form: Liquid