Invitrogen™ ACTA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5117294

Catalog No. PIPA5117294

Description

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The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Specifications

• Antigen: Actin, alpha skeletal muscle
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Acta1
• Gene Alias: 0610041G09Rik; AA959943; AAT6; ACTA; Acta1; ACTA1 protein; Acta2; Acta-2; actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 2, smooth muscle; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; Acts; ACTSA; Actsk-1; Actvs; alpha actin; alpha actin 2; Alpha-actin-1; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-smooth muscle actin; ASMA; a-SMA; cell growth-inhibiting gene 46 protein; CFTD; CFTD1; CFTDM; cytoplasmic beta-actin; GIG46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, alpha skeletal muscle; LOW QUALITY PROTEIN: actin, aortic smooth muscle; MPFD; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; SMalphaA; smooth muscle alpha-actin; unnamed protein product
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11459, 11475, 58, 59
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.43 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P62736, P62737, P68133, P68134
• Gene Symbols: Acta1, ACTA2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human alpha Skeletal Muscle Actin. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG