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Invitrogen™ Actin-like 7A Polyclonal Antibody
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Catalog No. PIPA530411
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PIPA530411 100 μL
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Catalog No. PIPA530411 Supplier Invitrogen™ Supplier No. PA530411
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Mouse (91%), Rat (92%), Chimpanzee (98%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Actin-like 7A
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene ACTL7A
Gene Accession No. Q9Y615
Gene Alias actin like 7A; actin-like 7a; actin-like 7-alpha; actin-like protein 7A; actin-like Tact2; actin-like-7-alpha; ACTL7A; Arp7a; Tact2; T-actin 2; T-actin-2; testicular secretory protein Li 3; testis-specific actin-2
Gene Symbols ACTL7A
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ACTL7A. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10881
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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