Invitrogen™ Actin-like 7A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531304

Catalog No. PIPA531304

Description

Recommended positive controls: NIH-3T3. Predicted reactivity: Mouse (84%), Rat (85%), Chimpanzee (99%), Bovine (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.

Specifications

• Antigen: Actin-like 7A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACTL7A
• Gene Alias: actin like 7A; actin-like 7a; actin-like 7-alpha; actin-like protein 7A; actin-like Tact2; actin-like-7-alpha; ACTL7A; Arp7a; Tact2; T-actin 2; T-actin-2; testicular secretory protein Li 3; testis-specific actin-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10881, 11470
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9QY84, Q9Y615
• Gene Symbols: ACTL7A
• Immunogen: Recombinant protein encompassing a sequence within the center region of human ACTL7A. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG