Invitrogen™ Actin-like 7B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544089

Catalog No. PIPA544089

Description

Peptide sequence: KLITIGQERF RCSEMLFQPS LAGSTQPGLP ELTAACLGRC QDTGFKEEMA Sequence homology: Cow: 77%; Dog: 83%; Human: 100%; Mouse: 85%; Rat: 92%.

The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene, and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.

Specifications

• Antigen: Actin-like 7B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACTL7B
• Gene Alias: actin like 7B; actin-like 7B; actin-like 7-beta; actin-like protein 7B; Actin-like-7-beta; ACTL7B; MGC151192; MGC151194; RP11-3J11.2; Tact1; t-actin 1; T-actin-1; testis tissue sperm-binding protein Li 43a; testis-specific actin-1; Unknown (protein for MGC:134108)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10880
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9Y614
• Gene Symbols: ACTL7B
• Immunogen: Synthetic peptide directed towards the middle region of human ACTL7B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG