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Invitrogen™ Actin-like 8 Polyclonal Antibody
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Catalog No. PIPA5110929
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100 μL
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PIPA5110929 100 μL
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Catalog No. PIPA5110929 Supplier Invitrogen™ Supplier No. PA5110929
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Rabbit Polyclonal Antibody

Immunogen sequence: MAARTVIIDH GSGFLKAGTA GWNEPQMVFP NIVNYLPCKE NPGPSYARRR VSLGIDICHP DTFSYPIERG RILNWEGVQY LWSFVLENHR REQ Highest antigen sequence indentity to the following orthologs: Mouse - 31%, Rat - 33%.

Actin-like protein 8 (ACTL8), also known as Cancer/Testis Antigen 57 (CT57), is part of the cancer/testis antigen (CTA) family. It is primarily expressed in the testes but aberrantly overexpressed in various cancers, including lung adenocarcinoma, endometrial cancer, and colorectal cancer. ACTL8's overexpression is associated with enhanced cell mobility, proliferation, and colony formation, contributing to tumor growth and poor prognosis. The gene is believed to play a critical role in oncogenesis and is being investigated as a potential therapeutic target due to its involvement in tumorigenic processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Actin-like 8
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ACTL8
Gene Accession No. Q9H568
Gene Alias actin like 8; actin like protein; actin-like 8; actin-like protein 8; ACTL8; Cancer/testis antigen 57; CT57
Gene Symbols ACTL8
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human Actin-like 8. Recombinant protein control fragment (Product #RP-94109).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 81569
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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