ACTL7B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8817	Proteintech Group Inc 135371AP150UL	150 μL

Description

The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene, and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predomitly in the testis, however, its exact function is not known.

Specifications

• Antigen: ACTL7B
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q4QR76, Q9QY83, Q9Y614
• Gene ID (Entrez): 10880, 11471, 313183
• Immunogen: ACTL7B Fusion Protein Ag4460
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ACTL7B

• Concentration: 0.21 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Actin like 7 beta, actin like 7B, Actin like protein 7B, ACTL7B
• Gene Symbols: Actl7b
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody