Invitrogen™ ACTR1A Monoclonal Antibody (3E5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA520935

Catalog No. PIMA520935

Description

Peptide Sequence: LVFAIQKSDM DLRRTLFSNI VLSGGSTLFK GFGDRLLSEV KKLAPKDVKI RISAPQERLY STWIGGSILA SLDTFKKMWV SKKEYEEDGA RSIHRKT.

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

Specifications

• Antigen: ACTR1A
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P61163
• Gene Symbols: ACTR1A
• Immunogen: ACTR1A (NP_005727, 279 a.a. ~ 375 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA
• Clone: 3E5
• Conjugate: Unconjugated
• Gene: ACTR1A
• Gene Alias: actin related protein 1A; actin-related protein 1 alpha; actin-related protein 1 homolog A; actin-RPV; ACTR1A; actr1a {ECO:0000250; alpha-Arp1; alpha-centractin; ARP1; ARP1 actin related protein 1 homolog A; ARP1 actin-related protein 1 homolog A, centractin alpha; ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); ARP1 actin-related protein 1A, centractin alpha; Arp1 centractin alpha; Arp1 contractin alpha; Arp1A; centractin; Centrosome-associated actin homolog; CTRN1; FLJ52695; FLJ52800; FLJ55002; UniProtKB:P61163}; yeast homolog A
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10121
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid