Invitrogen™ ACTR1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530355

Catalog No. PIPA530355

Description

Recommended positive controls: IMR32, mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.

Specifications

• Antigen: ACTR1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Actr1b
• Gene Alias: 2310066K23Rik; AA960180; Actin-related protein 1B; Actr1b; AI851923; ARP1; ARP1 actin-related protein 1 homolog B, centractin beta; ARP1 actin-related protein 1 homolog B, centractin beta (yeast); ARP1 actin-related protein 1B, centractin beta; Arp1b; Beta-centractin; centractin beta; CTRN2; PC3; yeast homolog B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10120, 226977
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.69 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P42025, Q8R5C5
• Gene Symbols: Actr1b
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 181 of Human Beta centractin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov