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Invitrogen™ ACVR1 Recombinant Rabbit Monoclonal Antibody (1J7G4)
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Catalog No. PIMA537901
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100 μL
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PIMA537901 100 μL
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Catalog No. PIMA537901 Supplier Invitrogen™ Supplier No. MA537901
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: 293T, A-549, MCF7, Mouse brain, Rat testis, Rat brain Immunogen sequence: VLWEVARRMV SNGIVEDYKP PFYDVVPNDP SFEDMRKVVC VDQQRPNIPN RWFSDPTLTS LAKLMKECWY QNPSARLTAL RIKKTLTKID NSLDKLKTDC.

Activin A receptor, type I (ACVR1) belongs to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. ACVR1 signals a specific transcriptional response in concert with activin type II receptors. The ACVR1 gene encodes activin A type I receptor, which signals a particular transcriptional response in concert with activin type II receptors. Mutations in ACVR1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR1
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 1J7G4
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3
Gene ACVR1
Gene Accession No. P37172, P80201, Q04771
Gene Alias activin A receptor type 1; activin A receptor type I; activin A receptor, type 1; activin A receptor, type I; activin A receptor, type II-like kinase 2; activin receptor I precursor; activin receptor type I; Activin receptor type-1; activin receptor-like kinase 2; activin type I receptor; ACTRI; ActR-I; ActRIA; Acvr; ACVR1; ACVR1A; ACVRLK2; ALK2; Alk-2; ALK2-B; Alk8; ATVR1; D330013D15Rik; FOP; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor; serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; Tgfb1; Tsk7L; TSK-7L; TSRI; TSR-I; type I TGF B receptor
Gene Symbols ACVR1
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11477, 79558, 90
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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