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Invitrogen™ ACVR1C Polyclonal Antibody
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Catalog No. PIPA5102319
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100 μL
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PIPA5102319 100 μL
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Catalog No. PIPA5102319 Supplier Invitrogen™ Supplier No. PA5102319
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ACVR1C.

ACVR1C, a serine/threonine protein kinase, is a type I receptor for the TGFB family of signaling molecules. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors. ACVR1C is a receptor for activin AB, activin B and NODAL. This protein plays a role in cell differentiation, growth arrest and apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR1C
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ACVR1C
Gene Accession No. P70539, Q8K348, Q8NER5
Gene Alias activin A receptor type 1C; activin A receptor type IC; activin A receptor, type IC; activin receptor type IC; Activin receptor type-1C; activin receptor-like kinase 7; ACTRI; ACTR-IC; ACVR1A; acvr1c; acvr1c {ECO:0000312; ACVRLK2; ACVRLK7; ALK2; Alk7; ALK-7; C230097P10; EMBL:AAC52803.1}; FOP; habrec1; SKR1; TGF-beta type 1 receptor; TSRI
Gene Symbols ACVR1C
Host Species Rabbit
Immunogen A synthesized peptide derived from human ACVR1C(Accession Q8NER5), corresponding to amino acid residues P417-A467.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 130399, 245921, 269275
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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