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Invitrogen™ ACVR1C Polyclonal Antibody
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Catalog No. PIPA533317
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50 μg
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PIPA533317 50 μg
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Catalog No. PIPA533317 Supplier Invitrogen™ Supplier No. PA533317
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Bovine, Bat, Pig (100%); Marmoset, Elephant, Panda, Horse, Rabbit (94%); Opossum, Turkey, Chicken, Platypus (88%). Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.

ACVR1C, a serine/threonine protein kinase, is a type I receptor for the TGFB family of signaling molecules. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors. ACVR1C is a receptor for activin AB, activin B and NODAL. This protein plays a role in cell differentiation, growth arrest and apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR1C
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene ACVR1C
Gene Accession No. Q8NER5
Gene Alias activin A receptor type 1C; activin A receptor type IC; activin A receptor, type IC; activin receptor type IC; Activin receptor type-1C; activin receptor-like kinase 7; ACTRI; ACTR-IC; ACVR1A; acvr1c; acvr1c {ECO:0000312; ACVRLK2; ACVRLK7; ALK2; Alk7; ALK-7; C230097P10; EMBL:AAC52803.1}; FOP; habrec1; SKR1; TGF-beta type 1 receptor; TSRI
Gene Symbols ACVR1C
Host Species Rabbit
Immunogen Synthetic 16 amino acid peptide from internal region of human ACVR1C.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100156756, 130399, 536380
Target Species Bat, Bovine, Human, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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