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ACVR2A Monoclonal Antibody (149/1), Invitrogen™

Catalog No. PIMA191751
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100 μg
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Catalog No. Quantity
PIMA191751 100 μg
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Catalog No. PIMA191751 Supplier Thermo Scientific Supplier No. MA191751

Description

Mouse Monoclonal Antibody

MA1-91751 detects Activin receptor type II from human samples.

Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases. ACVR2A is involved in the activin and myostatin signaling pathway. (ACVR2A Aliases: ACVR2, ACTRII). These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2A
Applications Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 149/1
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene ACVR2A
Gene Accession No. P27037, P38444
Gene Alias activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor
Gene Symbols ACVR2A
Host Species Mouse
Immunogen Recombinant intracellular kinase domain of the human type 2 activin receptor
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29263, 92
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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