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Invitrogen™ ACVR2A Monoclonal Antibody (C11)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA543988
This item is not returnable.
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Description
ACVR2A Monoclonal Antibody for Western Blot, IHC (P)
Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases. ACVR2A is involved in the activin and myostatin signaling pathway. (ACVR2A Aliases: ACVR2, ACTRII). These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
Specifications
ACVR2A | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
P27037 | |
ACVR2A | |
Recombinant protein Activin A Receptor Type II A. The antigen corresponds to amino acid range 20-135 of the target protein. | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
Immunohistochemistry (Paraffin), Western Blot | |
C11 | |
Unconjugated | |
ACVR2A | |
activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor | |
Mouse | |
Protein A/G | |
RUO | |
92 | |
-20°C | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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