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Invitrogen™ ACVR2A Polyclonal Antibody
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Catalog No. PIPA5114823
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100 μL
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PIPA5114823 100 μL
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Catalog No. PIPA5114823 Supplier Invitrogen™ Supplier No. PA5114823
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ACVR2A.

Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases. ACVR2A is involved in the activin and myostatin signaling pathway. (ACVR2A Aliases: ACVR2, ACTRII). These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2A
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene ACVR2A
Gene Accession No. P27037, P27038, P38444
Gene Alias activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor
Gene Symbols ACVR2A
Host Species Rabbit
Immunogen A synthesized peptide derived from human ACVR2A(Accession P27037), corresponding to amino acid residues V284-L334.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11480, 29263, 92
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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