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Invitrogen™ ACVR2A Polyclonal Antibody
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Catalog No. PIPA5119790
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100 μL
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PIPA5119790 100 μL
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Catalog No. PIPA5119790 Supplier Invitrogen™ Supplier No. PA5119790
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Description

Rabbit Polyclonal Antibody

Positive Control: SW480 cell lysate, K562 cell lysate, HepG2 cell lysate, mouse kidney tissue lysate, mouse testis tissue lysate, rat testis tissue lysate. Subcellular Location: Membrane.

Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases. ACVR2A is involved in the activin and myostatin signaling pathway. (ACVR2A Aliases: ACVR2, ACTRII). These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2A
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene ACVR2A
Gene Accession No. P27037, P27038, P38444
Gene Alias activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor
Gene Symbols ACVR2A
Host Species Rabbit
Immunogen Synthetic peptide within human ACVR2A aa 470-513.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11480, 29263, 92
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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