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Invitrogen™ ACVR2B Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547005

Catalog No. PIPA547005


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Description

Description

In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse Activin RIIB is observed, and less than 1% cross-reactivity with recombinant human (rh) Activin RIIA, rhActivin RIA, and rhActivin RIB is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ACVR2B
Polyclonal
Unconjugated
ACVR2B
activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Goat
Antigen affinity chromatography
RUO
93
-20°C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Neutralization, Western Blot
0.2 mg/mL
PBS with 5% trehalose and No Preservative
Q13705
ACVR2B
Mouse myeloma cell line NS0-derived recombinant human Activin RIIB Ser19-Thr134.
100 μg
Primary
Human
Antibody
IgG
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