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Invitrogen™ ACVR2B Polyclonal Antibody

Catalog No. PIPA120175
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25 μg
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Catalog No. Quantity
PIPA120175 25 μg
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Catalog No. PIPA120175 Supplier Invitrogen™ Supplier No. PA120175

Description

Goat Polyclonal Antibody

Neutralization: when used at a 1-3 μg/mL this antibody will block 50% of the binding of 30 ng/mL recombinant human activin A to immobilized recombinant human activin receptor IIB/Fc chimera (100 μL of a 0.5 μg/mL solution coating each well) in an ELISA assay.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2B
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ACVR2B
Gene Accession No. Q13705
Gene Alias activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Gene Symbols ACVR2B
Host Species Goat
Immunogen Purified, NSO-derived, recombinant human activin receptor IIB extracellular domain.
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 93
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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