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Invitrogen™ ACVRL1 Monoclonal Antibody (05)
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Catalog No. PIMA530038
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Quantity:
100 μL
Catalog No. Quantity
PIMA530038 100 μL
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Catalog No. PIMA530038

Supplier: Invitrogen™ MA530038

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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human ALK-1/ACVRL1.

Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2. Mutations in ACVRL1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVRL1
Applications ELISA
Classification Monoclonal
Clone 05
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene ACVRL1
Gene Accession No. P37023
Gene Alias activin A receptor like type 1; activin A receptor type II-like 1; activin A receptor type IL; activin A receptor, type II-like 1; activin A receptor, type II-like kinase 1; Activin receptor like kinase 1; activin receptor-like kinase 1; activin receptor-like kinase-1; Acvrl1; Acvrlk1; AI115505; AI427544; ALK1; ALK-1; HHT; HHT2; ORW2; R3; R-3; Serine/threonine-protein kinase receptor R3; SETHKIR; SKR3; TGF-B superfamily receptor type I; TSR-I
Gene Symbols ACVRL1
Host Species Mouse
Immunogen Recombinant Human ALK-1/ACVRL1 Protein (Met1-Gln118).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 94
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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